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- PA/CDDP PA/CDDP
- RA/CDDP RA/CDDP
- CoC1/cDDP CoC1/cDDP
- 人肺腺癌细胞系A549/CDDP lung adenocareinoma cell line
- CMN对CDDP抗肿瘤细胞增殖作用无明显影响。 Moreover,CMN does not influence anti-proliferation of CDDP on tumor cells.
- 结果提示,20 ug/ml与13 ug/ml CA对CDDP有增敏作用。 The cytotoxic effects of CDDP plus 20ug/ml, 13ug/ml CA were statistically significantly more cytotoxic than Cdd?
- 醋酸甲羟孕酮对卵巢癌CoC1/cDDP细胞增殖和耐药逆转的影响 Study of the inhibitory growth and reversing effect DDP resistance of medroxyprogesterone acetate on the ovarian cancer cell line CoC1/cDDP
- CMN预处理可减轻CDDP引起的肾脏系数升高及BUN、CRE水平升高; CMN pretreatment at lower doses would alleviate the CDDP-induced increases of BUN,CRE,and inhibit the increases of MDA formation in kidney cortex homogenate,and enhance the decreases of contents of GSH and activities of GSH-Px in kidney cortex homogenate in rats.
- CMN连续给予大鼠灌胃3 d,第2天灌胃后1 h腹腔注射CDDP(5.5 mg/kg)。 Animals received CMN by gavage for 3 days,and after 1 h of the second administration of CMC. Animals were intraperitoneally administration of CDDP(5.5 mg/kg).
- 较高剂量CMN未见防护CDDP所致肾毒性的作用,其原因可能与其助氧化作用有关。 CMN at higher doses would be a co-oxidant and not protect against CDDP-induced nephrotoxicity and oxidative stress.
- 另外,CMN对CDDP体外抑制肿瘤细胞SCaBER或HO-8910PM细胞增殖没有明显影响。 CDDP+40 mg/kg CMN: animals were received 40mg/kg CMN and the treatment was the same as that of the group (4);
- 免疫细胞化学显示,H446/CDDP、H446细胞MPG蛋白表达呈阳性,均表达于细胞核。 MPG protein was detected only in the nucleus of H446/CDDP multidrug-resistance cell line and H446 parental cell line.
- 目的研究姜黄素(CMN)对顺铂(CDDP)所致肾损害的防护作用,并探讨其可能机制。 Objective To investigate the protective effect of curcumin(CMN) on cisplatin(CDDP)-induced nephrotoxicity in rats and plausible mechanism.
- 细胞培养及逐步递增顺铂浓度、间歇作用体外诱导法建立耐药细胞株 BGC-823/cDDP; Cell culture and gradually increasing does ofcisplatin and intermittent administration was used to establish cisplatinresistance cell line BGC823/cDDP;
- 目的 探讨奥曲肽(OCT)对三种常见胃癌化疗药物(5-Fu、MMC、CDDP)体外抗肿瘤特性的影响。 Objective To evaluate the influence of octreotide(OCT) on anti-tumor characteristics of three common chemotherapeutic drugs for gastric cancer(5-Fu, MMC and CDD) in vitro.
- 目的:研究奥沙利铂(L-OHP)或顺铂(CDDP)对人胃癌细胞株BGC-823生长的抑制作用以及Livin基因表达的变化。 Objective:To investigate the growth inhibition of Oxaliplatin(L-OHP) or Cisplatin(CDDP) in vitro and Livin gene expression induced by the two platinum compounds on human gastric cancer cell line(BGC-823).
- 每例均行 CAG,贲门癌灌注动脉多取 LGA+CA,胃体窦癌为 CHA 或 CA,也可为 LGA,用药绝大多数为 FDM(5FU+CDDP+MMC)。 in addition LGA+CA were al- ways performed in cases of carcinoma of cardiac end of stomach so as CHA,either CA or LGA for gastric antrum carcinomas; while FDM(5Fu+CDDDP+MMC)were the drugs used for the majority of the patients.
- 应用半定量RT-PCR方法检验小细胞肺癌SH77、大细胞肺癌H460、肺腺癌SPC-A-1和SPC-A-1/cDDP等细胞株中该基因mRNA的表达。 The mRNA levels of this gene were determined in SCLC cell line SH77 ,big cell lung cancer cell line H460,lung adenocarcinoma cell line SPC A 1 and SPC A 1/CDDP using semi quantitative RT PCR assay.
- 行支气管动脉插管,经导管灌入CDDP 80-100 mg、MMC 10 mg后,再将ADM 30 mg和2-10 ml碘化油(平均4.65 ml)混悬剂化疗栓塞。 After perfusion of 80 - 100 mg CDDP and 10 mg MMC, embolization with a mixture of 30 mg ADM and 2 - 10 mg Lipidol was performed.
- 反转录病毒载体-HSV-tk-GCV系统进行脑胶质瘤基因治疗的实验研究以及GCV、CDDP诱导转导、非转导C6胶质瘤细胞凋亡的实验研究 Experimental Study of Retrovirus Vector-HSV-tk-GCV System Gene Therapy for Glioma and Effects of GCV, Cisplatin on the Induction of Apoptosis in Transduced and Nontransduced C6 Glioma Cells